| Adobe Acrobat Reader DC | PDF Viewer | Office and Productivity | Free |
| BlackBaud CRM (WREN) | Donorship and Fundraising | Fundraising | University Licensed |
| Alertus Desktop Notification | Emergency Alerts and Notification System | Security | University Licensed |
| AutoDesk | Design and drafting software used by architects, designers, and planners. | Design & Drafting | University Licensed |
| Banner Admin Production | Allows authorized users to perform various administrative actions pertaining to finance, financial aid, HR, and obtaining student information. | Office and Productivity | University Licensed |
| Box | File Sharing and Storage | File Sharing | University Licensed |
| Box Drive | Add-on to Box which allows access through Windows Explorer or Mac Finder | File Sharing | Free |
| Chem BioDraw Ultra | Chemical Structures Drawing Software | Chemistry | University Licensed |
| DUO | Two factor authentication (2F) software that runs on your PC, phone, or mobile device | Security | University Licensed |
| Eduroam | William & Mary's Secure Wireless Network | Security and Networking | University Licensed |
| Global Protect (VPN) | Virtual Private Network to allow secure remote access | Security and Networking | University Licensed |
| Google Chrome | A cross-platform web browser by Google | Internet and Email | Free |
| LinkedIn Learning | Online education and training platform. | Training | University Licensed |
| Maple | Math & Statistical Problem Solving Tool | Math & Statistics | University Licensed |
| Matlab | MATLAB is a high-level language and interactive environment that enables you to perform computational and visualization intensive tasks. | Statistics | University Licensed |
| MAXQDA | MAXQDA is a Qualitative Research Analysis Tool | Qualitative Analysis Tools | University Licensed |
| Office 365 | Suite of cloud-based productivity and collaboration applications that integrates all Microsoft's existing online applications (Word, Excel, PowerPoint, OneNote, Outlook, Publisher, Sway, and Access) into a cloud service | Office and Productivity | University Licensed |
| Microsoft Teams | Chat and Collaboration | Office Productivity | University Licensed |
| Minitab for Windows | Minitab is a statistics package | Statistics | Subscription Fees |
| Mitel Connect | Interface that extends the features of your campus phone | Office and Productivity | University Licensed |
| Mozilla Firefox | A cross-platform web browser by Mozilla | Internet and Email | Free |
| Panopto | Video capturing software integrated into Blackboard | Classroom support | University Licensed |
| PCModel | Chemistry Molecular Modelling | Chemistry | University Licensed |
| Poly Lens | Poly Headset | Office Hardware | No license needed |
| SAS | Statistical Analytics, Artificial Intelligence and Data Management Software | Math & Statistics | University Licensed |
| SPSS | Statistical Package for the Social Sciences | Math & Statistics | University Licensed |
| Stata | General purpose Statistical Software | Statistics | Subscription Fees |
| Wolfram Mathematica | Math, Statistical and Computational Software | Math, Statistics, and Computational Software | University Licensed |
| Zoom | Cloud-based video communications app that allows you to set up virtual video and audio conferencing, webinars, live chats, screen-sharing, and other collaborative capabilities | Office and Productivity, Teaching and Learning | University Licensed |
